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Home Antibody All anti-ORC2L antibodies

Anti-ORC2L Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308075
  • Rabbit polyclonal antibody to ORC2 (origin recognition complex, subunit 2-like (yeast))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416811) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for ORC2L (NM_006190)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 208 and 479 of ORC2 (Uniprot ID#Q13416)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Bovine) Concentration0.45mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 66kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (84%), Bovine (92%)

Reference Data

Target NameHomo sapiens origin recognition complex, subunit 2 (ORC2), transcript variant 1
Alternative NameORC2L
Database LinkNP_006181
Entrez Gene 4999 Human
Entrez Gene 18393 Mouse
FunctionThe origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3L, -4L, and -5L. It also interacts with CDC45L and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. [provided by RefSeq]
Related PathwayStem cell - PluripotencyTranscription Factors Cell cycle

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). . A: Raji. . 7.5% SDS PAGE. . ORC2 antibody. . TA308075 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded CL1-0 Xenograft, using ORC2(TA308075) antibody at 1:100 dilution.

 

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