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Also for KCNJ3 (NM_002239)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 248 and 501 of GIRK1|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 3 (KCNJ3), transcript variant 1|
|GIRK1; KGA; KIR3.1|
|Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A:A431 B: H1299 C: Hela (anti-KCNJ3 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded DU145 xenograft, using GIRK1(anti-KCNJ3 antibody) antibody at 1:100 dilution.