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Home Antibody All anti-PTS antibodies

Anti-PTS Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308040
  • Rabbit Polyclonal antibody to PTS (6-pyruvoyltetrahydropterin synthase)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400120) , 20ug Explanation
100ul $325 3-7 Days
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WB(2)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 145 of PTS (Uniprot ID#Q03393)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 16kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Bovine (84%)

Reference Data

Target NameHomo sapiens 6-pyruvoyltetrahydropterin synthase (PTS)
Alternative NamePTPS
Database LinkNP_000308
Entrez Gene 5805 Human
FunctionThe enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq]
Related PathwayDruggable Genome Folate biosynthesisMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (50 ug of whole cell lysate). A: mouse stomach. 15% SDS PAGE. TA308040 diluted at 1:1000.
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Sample (30 ug of whole cell lysate). A: H1299. 15% SDS PAGE. TA308040 diluted at 1:1000.
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Immunohistochemical analysis of paraffin-embedded Hepatoma, using PTS(TA308040) antibody at 1:500 dilution.
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Immunofluorescence analysis of methanol-fixed HeLa, using PTS(TA308040) antibody at 1:100 dilution.
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