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Home Antibody All anti-AKR1C1 antibodies

Anti-AKR1C1 Antibody

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SKU Description Amount Price Availability*  
TA308032 Rabbit Polyclonal antibody to AKR1C1 (aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)) 100ul $325 3-7 Days
LC419968 AKR1C1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(2)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 22 and 248 of AKR1C1 (Uniprot ID#Q04828)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 37kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens aldo-keto reductase family 1, member C1 (AKR1C1)
Alternative Name2-ALPHA-HSD; 20-ALPHA-HSD; C9; DD1; DD1/DD2; DDH; DDH1; H-37; HAKRC; HBAB; MBAB
Database LinkNP_001344
Entrez Gene 1645 Human
FunctionThis gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq]
Related PathwayDruggable Genome Metabolism of xenobiotics by cytochrome P450

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample(30 ug whole cell lysate). A:Raji . 10% SDS PAGE. TA308032 diluted at 1:1000
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AKR1C1 antibody detects AKR1C1 protein by Western blot analysis. A. 50 ug mouse liver lysate/extract. 10 % SDS-PAGE. AKR1C1 antibody (TA308032) dilution: 1:1000
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Immunohistochemical analysis of paraffin-embedded MDA-MB-468 xenograft , using AKR1C1(TA308032) antibody at 1:500 dilution.
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Immunofluorescence analysis of methanol-fixed A431, using AKR1C1(TA308032) antibody at 1:200 dilution.
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