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Home Antibody All anti-TPM2 antibodies

Anti-TPM2 Antibody


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SKU Description Amount Price Availability*  
TA308017 Rabbit polyclonal antibody to Tropomyosin 2 (tropomyosin 2 (beta)) 100ul $325 2 Weeks
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OriGene Data

ImmunogenRecombinant fragment contain a sequence corresponding to a region within amino acids 1 and 234 of Tropomyosin 2 (Uniprot ID#P07951)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Bovine, Xenopus tropicalis) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 33kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (86%), Rat (99%), Bovine (92%), Xenopus tropicalis (85%)

Reference Data

Target NameHomo sapiens tropomyosin 2 (beta) (TPM2), transcript variant 3
Alternative NameAMCD1; DA1; DA2B; NEM4; TMSB; DA1; DA2B; TMSB; OTTHUMP00000021357; arthrogryposis multiplex congenital, distal, type 1; tropomyosin 2 (beta)
Database LinkNP_001139294
Entrez Gene 7169 Human
Entrez Gene 22004 Mouse
Entrez Gene 500450 Rat
FunctionThis gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Related Pathway Cardiac muscle contractionHypertrophic cardiomyopathy (HCM)Dilated cardiomyopathy

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: HeLa. 10% SDS PAGE. TA308017 diluted at 1:1000

IHC Image
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using Tropomyosin 2(TA308017) antibody at 1:100 dilution.


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