Home Antibody All anti-NDUFS2 antibodies
Also for NDUFS2 (NM_004550)
|Recombinant fragment corresponding to a region within amino acids 200 and 430 of NDUFS2 (Uniprot ID#O75306)|
|Human, Mouse (Predicted: Chimpanzee)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:10000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Chimpanzee (100%)
|Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) (NDUFS2), transcript variant 1|
Entrez Gene 4720 Human
Entrez Gene 226646 Mouse
|Mitochondrial complex I (NADH-ubiquinone reductase; EC 22.214.171.124) is the first multimeric complex of the respiratory chain that catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mammalian mitochondrial complex I is an assembly of at least 43 different subunits. Seven of the subunits are encoded by the mitochondrial genome; the remainder are the products of nuclear genes. The iron-sulfur protein (IP) fraction of complex I is made up of 7 subunits, including NDUFS2. See NDUFS1 (MIM 157655).[supplied by OMIM]|
| Oxidative phosphorylationMetabolic pathwaysAlzheimer's diseaseParkinson's diseaseHuntington's disease|
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Sample (50 ug of whole cell lysate). A: Mouse brain. 10% SDS PAGE. TA307995 diluted at 1:10000.
Sample (30 ug of whole cell lysate). A: 293T. B: A431 . C: JurKat. D: Raji. 10% SDS PAGE. TA307995 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Colon ca, using NDUFS2(TA307995) antibody at 1:250 dilution.
NDUFS2 antibody detects NDUFS2 protein at mitochondria by immunofluorescent analysis. Sample: HeLa cells were fixed in 2% paraformaldehyde/culture medium at 37Ã¢ for 30 min. Green: NDUFS2 protein stained by NDUFS2 antibody (TA307995) diluted at 1:500. Blu