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Home Antibody All anti-AKR1C4 antibodies

Anti-AKR1C4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307983
  • Rabbit polyclonal antibody to HSD3a (aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419725) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for AKR1C4 (NM_001818)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 217 of HSD3a (Uniprot ID#P17516)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.83mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 37kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens aldo-keto reductase family 1, member C4 (AKR1C4)
Alternative Name3-alpha-HSD; C11; CDR; CHDR; DD-4; DD4; HAKRA
Database LinkNP_001809
Entrez Gene 1109 Human
FunctionThis gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq]
Related PathwayDruggable Genome Primary bile acid biosynthesisC21-Steroid hormone metabolismAndrogen and estrogen metabolismMetabolism of xenobiotics by cytochrome P450Metabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Hela. 10% SDS PAGE. HSD3a antibody. TA307983 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded gastric ca, using AKR1C4(TA307983) antibody at 1:100 dilution.
IF Image
HSD3a antibody [N1C2] detects HSD3a protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: HSD3a protein stained by HSD3a antibody [N1C2] (TA307983) diluted at 1:500. B

 

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