Home Antibody All anti-GSTA4 antibodies
Also for GSTA4 (NM_001512)
|Recombinant fragment corresponding to a region within amino acids 1 and 222 of GSTA4 (Uniprot ID#O15217)|
|Human (Predicted: Cow)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Cow (94%)
|Homo sapiens glutathione S-transferase alpha 4 (GSTA4)|
Entrez Gene 2941 Human
|Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. [provided by RefSeq]|
| Glutathione metabolismMetabolism of xenobiotics by cytochrome P450Drug metabolism - cytochrome P450|
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Sample (30 ug of whole cell lysate). A: 293T. 12% SDS PAGE. GST A4 antibody. TA307976 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using GSTA4(TA307976) antibody at 1:100 dilution.