Home Antibody All anti-RAMP1 antibodies
Also for RAMP1 (NM_005855)
|Synthetic peptide corresponding to a region within amino acids 84 and 148 of RAMP1 (Uniprot ID#O60894)|
|Human (Predicted: Mouse, Rat, Xenopus Tropicalis, Pig, Guinea pig)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (93%), Rat (93%), Xenopus Tropicalis (87%), Pig (86%), Guinea pig (80%)
|Homo sapiens receptor (G protein-coupled) activity modifying protein 1 (RAMP1)|
|receptor (calcitonin) activity modifying protein 1; receptor-activity modifying protein 1; receptor (G protein-coupled) activity modifying protein 1|
Entrez Gene 10267 Human
Entrez Gene 51801 Mouse
Entrez Gene 58965 Rat
|The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. [provided by RefSeq]|
|TransmembraneDruggable Genome Vascular smooth muscle contraction|
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Sample (30 ug of whole cell lysate). A: Hep G2 . 12% SDS PAGE. TA307973 diluted at 1:1000.