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Home Antibody All anti-RAMP1 antibodies

Anti-RAMP1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307973
  • Rabbit polyclonal antibody to RAMP1 (receptor (G protein-coupled) activity modifying protein 1)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417025) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 84 and 148 of RAMP1 (Uniprot ID#O60894)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Xenopus Tropicalis, Pig, Guinea pig) Concentration0.87mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 17kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (93%), Rat (93%), Xenopus Tropicalis (87%), Pig (86%), Guinea pig (80%)

Reference Data

Target NameHomo sapiens receptor (G protein-coupled) activity modifying protein 1 (RAMP1)
Alternative Namereceptor (calcitonin) activity modifying protein 1; receptor-activity modifying protein 1; receptor (G protein-coupled) activity modifying protein 1
Database LinkNP_005846
Entrez Gene 10267 Human
Entrez Gene 51801 Mouse
Entrez Gene 58965 Rat
FunctionThe protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. [provided by RefSeq]
Related PathwayTransmembraneDruggable Genome Vascular smooth muscle contraction

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WB Image
Sample (30 ug of whole cell lysate). A: Hep G2 . 12% SDS PAGE. TA307973 diluted at 1:1000.

 

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