Home All anti-RAMP1 antibodies
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Also for RAMP1 (NM_005855)
|84 - 148 of Human RAMP1|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens receptor (G protein-coupled) activity modifying protein 1 (RAMP1)|
|receptor (calcitonin) activity modifying protein 1; receptor-activity modifying protein 1; receptor (G protein-coupled) activity modifying protein 1|
|The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. [provided by RefSeq]|
Signaling by GPCR
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A: HepG2 (anti-RAMP1 antibody diluted at 1:1000)