Home Antibody All anti-ATP6V1H antibodies
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Also for ATP6V1H (NM_213620)
|Recombinant fragment corresponding to a region within amino acids 169 and 444 of ATP6V1H (Uniprot ID#Q9UI12)|
|Human, Mouse (Predicted: Chicken, Pig, Xenopus laevis, Zebrafish, Bovine, Xenopus tropicalis)
||Lot dependent; please refer to CoA along with shipment
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Chicken (96%), Pig (99%), Xenopus laevis (94%), Zebrafish (91%), Bovine (98%), Xenopus tropicalis (94%)
|Homo sapiens ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H (ATP6V1H), transcript variant 3|
|CGI-11; MSTP042; NBP1; SFD; SFDalpha; SFDbeta; VMA13|
Entrez Gene 51606 Human
Entrez Gene 108664 Mouse
|This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the regulatory H subunit of the V1 domain which is required for catalysis of ATP but not the assembly of V-ATPase. Three alternatively spliced transcript variants encode two isoforms of the H subunit. [provided by RefSeq]|
| Oxidative phosphorylationMetabolic pathwaysLysosomeVibrio cholerae infectionEpithelial cell signaling in Helicobacter pylori infection|
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Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA307969 diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: Hela. 7.5% SDS PAGE. TA307969 diluted at 1:1000.