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Home Antibody All anti-FH antibodies

Anti-FH Antibody

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SKU Description Amount Price Availability*  
TA307962 Rabbit Polyclonal antibody to Fumarate hydratase (fumarate hydratase) 100ul $325 3-7 Days
LC400053 FH HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(3)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 89 and 365 of Fumarate hydratase (Uniprot ID#P07954)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:10000
Predicted MW Explanation 55kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens fumarate hydratase (FH)
Alternative NameFMRD; HLRCC; LRCC; MCL; MCUL1
Database LinkNP_000134
Entrez Gene 2271 Human
FunctionThe protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq]
Related PathwayDruggable Genome Citrate cycle (TCA cycle)Metabolic pathwaysPathways in cancerRenal cell carcinoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Fumarate hydratase antibody [N2C2], Internal detects FH protein by Western blot analysis. A. 50 ug mouse liver lysate/extract. 10% SDS-PAGE. Fumarate hydratase antibody [N2C2], Internal (TA307962) dilution: 1:1000.
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Sample (30 ug of whole cell lysate). A: 293T. B: A431 . 10% SDS PAGE. TA307962 diluted at 1:5000
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Fumarate hydratase antibody [N2C2], Internal detects Fumarate hydratase protein by Western blot analysis. A.50 ug rat liver lysate/extract. 10 % SDS-PAGE. Fumarate hydratase antibody [N2C2], Internal (TA307962) dilution: 1:5000
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Immunohistochemical analysis of paraffin-embedded OVCAR3 xenograft, using fumarate hydratase (TA307962) antibody at 1:500 dilution.
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Immunofluorescence analysis of methanol-fixed HeLa, using Fumarate hydratase(TA307962) antibody at 1:200 dilution.
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