Home Antibody All anti-FH antibodies
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 89 and 335 of fumarate hydratase|
|WB, IHC, IF
||WB:1:1000-1:10000; IHC:1:500; IF:1:100-1:200;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens fumarate hydratase (FH)|
|HLRCC; LRCC; MCL; MCUL1|
|The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A: 293T B: A431 (anti-FH antibody diluted at 1:5000)
Immunohistochemical analysis of paraffin-embedded OVCAR3 xenograft, using fumarate hydratase (anti-FH antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of methanol-fixed HeLa, using Fumarate hydratase(anti-FH antibody) antibody at 1:200 dilution.