Home Antibody All anti-ALDH1A2 antibodies
Also for ALDH1A2 (NM_170697)
|Recombinant fragment corresponding to a region within amino acids 278 and 518 of ALDH1A2 (Uniprot ID#O94788)|
|Human, Mouse (Predicted: Chicken, Rat, Xenopus laevis, Xenopus tropicalis)
||Lot dependent; please refer to CoA along with shipment
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Chicken (98%), Rat (98%), Xenopus laevis (91%), Xenopus tropicalis (92%)
|Homo sapiens aldehyde dehydrogenase 1 family, member A2 (ALDH1A2), transcript variant 3|
|RALDH(II); RALDH2; RALDH2-T|
Entrez Gene 8854 Human
Entrez Gene 19378 Mouse
Entrez Gene 116676 Rat
|This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]|
|Druggable Genome Retinol metabolismMetabolic pathways|
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Sample (50 ug of whole cell lysate). A: mouse liver. 7.5% SDS PAGE. TA307922 diluted at 1:10000.
Sample (30 ug of whole cell lysate). A: IMR32. 10% SDS PAGE. TA307922 diluted at 1:1000.