Home Antibody All anti-APRT antibodies
Also for APRT (NM_001030018)
|Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 84 of APRT (Uniprot ID#P07741)|
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens adenine phosphoribosyltransferase (APRT), transcript variant 2|
Entrez Gene 353 Human
|Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Druggable Genome Purine metabolismMetabolic pathways|
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APRT antibody detects APRT protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug A431 whole cell lysate/extract. 15 % SDS-PAGE. APRT antibody (TA307909) dilution: 1:1000
Immunohistochemical analysis of paraffin-embedded DLD-1 xenograft, using APRT(TA307909) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using APRT(TA307909) antibody at 1:200 dilution.