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Home Antibody All anti-APRT antibodies

Anti-APRT Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307909
  • Rabbit polyclonal antibody to APRT (adenine phosphoribosyltransferase)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC425509) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for APRT (NM_001030018)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant fragment contain a sequence corresponding to a region within amino acids 1 and 84 of APRT (Uniprot ID#P07741)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 15kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens adenine phosphoribosyltransferase (APRT), transcript variant 2
Alternative NameAMP; APRTD
Database LinkNP_001025189
Entrez Gene 353 Human
FunctionAdenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Related PathwayDruggable Genome Purine metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
APRT antibody detects APRT protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug A431 whole cell lysate/extract. 15 % SDS-PAGE. APRT antibody (TA307909) dilution: 1:1000
IHC Image
Immunohistochemical analysis of paraffin-embedded DLD-1 xenograft, using APRT(TA307909) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using APRT(TA307909) antibody at 1:200 dilution.

 

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