Home Antibody All anti-PEX19 antibodies
Also for PEX19 (NM_001131039)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 269 of PEX19|
|WB, IHC, IF
||WB:1:1000-1:10000; IHC:1:500; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens peroxisomal biogenesis factor 19 (PEX19), transcript variant 2|
|D1S2223E; FLJ55296; HK33; PMP1; PMPI; PXF; PXMP1; HK33; PMP1; PMPI; PXF; PXMP1; OTTHUMP00000031848; housekeeping gene, 33kD; peroxisomal farnesylated protein; peroxisomal biogenesis factor 19|
|This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A: Molt-4 (anti-PEX19 antibody diluted at 1:10000)
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using PEX19(anti-PEX19 antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed A549, using PEX19(anti-PEX19 antibody) antibody at 1:200 dilution.