Home Antibody All anti-AKAP12 antibodies
Also for AKAP12 (NM_005100)
|Synthetic peptide contain a sequence corresponding to a region within amino acids 1719 and 1782 of AKAP12|
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:100; IF:1:100-1:200;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens A kinase (PRKA) anchor protein 12 (AKAP12), transcript variant 1|
|The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]|
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Sample (30ug whole cell lysate) A:HeLa S3 (anti-AKAP12 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded serous OVCA, using AKAP12(anti-AKAP12 antibody) antibody at 1:100 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using AKAP12(anti-AKAP12 antibody) antibody at 1:200 dilution.