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Home Antibody All anti-DSC2 antibodies

Anti-DSC2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307897
  • Rabbit polyclonal antibody to Desmocollin 2 (desmocollin 2)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417636) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for DSC2 (NM_004949)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 480 and 676 of Desmocollin 2
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB:1:500-1:3000; IHC:1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens desmocollin 2 (DSC2), transcript variant Dsc2b
Alternative NameARVD11; CDHF2; DG2; DGII/III; DSC3
Database LinkNP_004940
FunctionThe protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq]
Related Pathway

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WB Image
Sample (30 ug of whole cell lysate) A: A431 (anti-DSC2 antibody diluted at 1:500)
IHC Image
Immunohistochemical analysis of paraffin-embedded OVCAR3 xenograft , using Desmocollin 2 (anti-DSC2 antibody) antibody at 1:500 dilution.

 

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