Home Antibody All anti-PRKAG2 antibodies
Also for PRKAG2 (NM_001040633)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 288 of AMPK gamma-2|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant c|
|AAKG; AAKG2; CMH6; H91620p; WPWS|
Entrez Gene 51422 Human
Entrez Gene 108099 Mouse
|AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Druggable Genome Insulin signaling pathwayAdipocytokine signaling pathwayHypertrophic cardiomyopathy (HCM)|
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Sample (30 ug of whole cell lysate) A: Hela S3 (anti-PRKAG2 antibody diluted at 1:1000)
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using AMPK gamma-2(anti-PRKAG2 antibody) antibody at 1:200 dilution.