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Anti-IQGAP1 Antibody EPR5221
Also for IQGAP1 (NM_003870)
|A synthetic peptide corresponding to residues in human IQGAP1 was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IHC-P: 1:500 - 1:1000; ICC: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens IQ motif containing GTPase activating protein 1 (IQGAP1)|
|HUMORFA01; p195; SAR1|
Entrez Gene 8826 Human
|IQGAP1 is a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, cell adhesion molecules, and several signaling molecules to regulate cell morphology and motility. Expression of IQGAP1 is upregulated by amplification in two gastric cancer cell lines.|
|Druggable Genome Adherens junctionRegulation of actin cytoskeleton|
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Western blot - IQGAP1 antibody [EPR5221]; All lanes : Anti-IQGAP1 antibody [EPR5221] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Cos-1 cell lysate.Lane 3 : HUVEC cell lysate.Lane 4 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 189 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - IQGAP1 antibody [EPR5221]; Immunohistochemical analysis of paraffin-embedded Human uterus tissue using TA307873 at a dilution of 1/500.