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Home Antibody All anti-IL8 antibodies

Anti-IL8 Antibody EPR1116(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307871
  • Rabbit monoclonal antibody against IL-8(clone EPR1116(2))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400198) , 20ug
100ul 325 In Stock
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WB(1)
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Also for IL8 (NM_000584)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human IL-8 was used as an immunogen.
Clone NameEPR1116(2) IsotypeTissue culture supernatant
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferDoes not react with Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens chemokine (C-X-C motif) ligand 8 (CXCL8)
Alternative NameGCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1
Database LinkNP_000575
FunctionChemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors (1). Interleukin-8 (IL-8) belongs to a family of small, structurally related cytokines similar to platelet factor 4. It is produced by phagocytes and mesenchymal cells exposed to inflammatory stimuli (e.g., interleukin-1 or tumor necrosis factor) and activates neutrophils inducing chemotaxis, exocytosis and the respiratory burst. In vivo, IL-8 elicits a massive neutrophil accumulation at the site of injection (2). It has recently been shown that IL-8, through its effects on the macrophage and endothelial cell, may be involved in the pathogenesis of atherosclerosis (3).
Related Pathway
Cytokine-cytokine receptor interaction
Senescence and Autophagy
Signaling by GPCR
Toll-like receptor signaling pathway

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WB Image
Western blot - IL8 antibody [EPR1116(2)]; Anti-IL8 antibody [EPR1116(2)] at 1/1000 dilution + IL8 recombinant protein at 10 µg.Predicted band size : 11 kDa.

 

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