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Anti-IL8 Antibody EPR1116(2)
|A synthetic peptide corresponding to residues in human IL-8 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
|Does not react with Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens interleukin 8 (IL8)|
|CXCL8; GCP-1; GCP1; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1|
|Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors (1). Interleukin-8 (IL-8) belongs to a family of small, structurally related cytokines similar to platelet factor 4. It is produced by phagocytes and mesenchymal cells exposed to inflammatory stimuli (e.g., interleukin-1 or tumor necrosis factor) and activates neutrophils inducing chemotaxis, exocytosis and the respiratory burst. In vivo, IL-8 elicits a massive neutrophil accumulation at the site of injection (2). It has recently been shown that IL-8, through its effects on the macrophage and endothelial cell, may be involved in the pathogenesis of atherosclerosis (3).|
Cytokine-cytokine receptor interaction
Senescence and Autophagy
Signaling by GPCR
Toll-like receptor signaling pathway
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Western blot - IL8 antibody [EPR1116(2)]; Anti-IL8 antibody [EPR1116(2)] at 1/1000 dilution + IL8 recombinant protein at 10 µg.Predicted band size : 11 kDa.