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Anti-FANCD2 Phospho Antibody EPR2278(2)
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Also for FANCD2 (NM_033084)
|A phospho specific peptide corresponding to residues surrounding Serine 1404 of human FANCD2 was used as an immunogen. This antibody only detects FANCD2 phosphorylated at Serine 1404.|
|Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.|
|Homo sapiens Fanconi anemia, complementation group D2 (FANCD2), transcript variant 1|
|FA-D2; FA4; FACD; FAD; FAD2; FANCD|
|The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group, FANCH, is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. FANCD2 is also known as Fanconi anemia group D2 protein. It is monoubiquitinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair.|
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Western blot analysis on HeLa cell lysates using anti-Phospho-FANCD2 (pS1404) RabMAb .