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 Home All anti-ATG12 antibodies

Anti-ATG12 Antibody EPR4799

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SKU Description Amount Price Availability*  
TA307833
  • Rabbit monoclonal antibody against Atg12(clone EPR4799)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401486) , 20ug
 100ul $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
 30ul
$100
$50*		 In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Atg12 was used as an immunogen.
Clone NameEPR4799 IsotypeRabbit IgG
Species ReactivityHuman Concentration
Guaranteed Application *WB, IHC Suggested DilutionsFC: 1:10-100, ICC: 1:100-250, IHC: 1:50-100, IP: 1:10-100, WB: 1:1,000-10,000,
BufferStore at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens autophagy related 12 (ATG12), transcript variant 1
Alternative NameAPG12; APG12L; FBR93; HAPG12
Database LinkNP_004698
FunctionAutophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. Atg12 is the human homolog of a yeast protein involved in autophagy (1). It is essential for Atg12 conjugation, and the ATG12-ATG5 conjugate is necessary to form autophagic vesicles (2). The E3-like activity of the Atg12-Atg5 conjugate potentiates the formation of Atg8-PE; making the autophagic pathway analogous to ubiquitin-like pathways where an E3 conjugation ligase is required (3).
Related Pathway

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WB Image
Western blot analysis on (A) THP-1, (B) HepG2, (C) Raji, and (D) fetal kidney lysates using anti-Atg12 RabMAb .
IHC Image
Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-Atg12 RabMAb .

 

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