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Home Antibody All anti-ATG12 antibodies

Anti-ATG12 Antibody EPR4800

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307830
  • Rabbit monoclonal antibody against Atg12(clone EPR4800)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401486) , 20ug Explanation
100ul 325 3-7 Days
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WB(2)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human Atg12 was used as an immunogen.
Clone NameEPR4800 IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:250 - 1:500; WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500
Predicted MW Explanation 15 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens autophagy related 12 (ATG12), transcript variant 1
Alternative NameAPG12; APG12L; FBR93; HAPG12
Database LinkNP_004698
Entrez Gene 9140 Human
FunctionAutophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. Atg12 is the human homolog of a yeast protein involved in autophagy (1). It is essential for Atg12 conjugation, and the Atg12-Atg5 conjugate is necessary to form autophagic vesicles (2). The E3-like activity of the Atg12-Atg5 conjugate potentiates the formation of Atg8-PE; making the autophagic pathway analogous to ubiquitin-like pathways where an E3 conjugation ligase is required (3).
Related Pathway Regulation of autophagyRIG-I-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Apg12 antibody [EPR4800]; All lanes : Anti-Apg12 antibody [EPR4800] at 1/1000 dilution.Lane 1 : Human fetal kidney lysate.Lane 2 : HepG2 lysate.Lane 3 : Raji lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 15 kDa.
WB Image
Western blot - Apg12 antibody [EPR4800]; All lanes : Anti-Apg12 antibody [EPR4800] at 1/1000 dilution.Lane 1 : Apg12 transfected 293T lysate .Lane 2 : Non-transfected 293T lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 15 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Apg12 antibody [EPR4800]; TA307830, at 1/250 dilution, staining Apg12 in paraffin-embedded Human breast carcinoma by Immunohistochemistry.

 

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