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Home Antibody All anti-A2M antibodies

Anti-A2M Antibody EPR4431

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SKU Description Amount Price Availability*  
TA307819
  • Rabbit monoclonal antibody against Alpha 2 Macroglobulin(clone EPR4431)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424975) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Alpha 2 Macroglobulin was used as an immunogen.
Clone NameEPR4431 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferpH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens alpha-2-macroglobulin (A2M)
Alternative NameA2MD; CPAMD5; FWP007; S863-7
Database LinkNP_000005
Entrez Gene 2 Human
FunctionAlpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. Alpha-2-macroglobulin is implicated in Alzheimer’s disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits (1).
Related PathwaySecreted ProteinDruggable Genome Complement and coagulation cascades

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-alpha 2 Macroglobulin antibody [EPR4431]; Anti-alpha 2 Macroglobulin antibody [EPR4431] at 1/1000 dilution + Human plasma lysate at 10 ug.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 163 kDa.
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