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Anti-A2M Antibody EPR4431
|A synthetic peptide corresponding to residues in human Alpha 2 Macroglobulin was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
|Homo sapiens alpha-2-macroglobulin (A2M)|
|A2MD; CPAMD5; FWP007; S863-7|
Entrez Gene 2 Human
|Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. Alpha-2-macroglobulin is implicated in Alzheimer’s disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits (1).|
|Secreted ProteinDruggable Genome Complement and coagulation cascades|
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Western blot - Anti-alpha 2 Macroglobulin antibody [EPR4431]; Anti-alpha 2 Macroglobulin antibody [EPR4431] at 1/1000 dilution + Human plasma lysate at 10 ug.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 163 kDa.