A synthetic peptide corresponding to residues in human Alpha 2 Macroglobulin was used as an immunogen.
Buffer
Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. Alpha-2-macroglobulin is implicated in Alzheimer’s disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits (1).
Related Pathway
Hemostasis
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