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Anti-A2M Antibody EPR4432
|A synthetic peptide corresponding to residues in human Alpha 2 Macroglobulin was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IHC-P: 1:500 - 1:1000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt,ICC or IP.
|Homo sapiens alpha-2-macroglobulin (A2M)|
|A2MD; CPAMD5; FWP007; S863-7|
Entrez Gene 2 Human
|Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. Alpha-2-macroglobulin is implicated in Alzheimer’s disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits (1).|
|Secreted ProteinDruggable Genome Complement and coagulation cascades|
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Western blot - alpha 2 Macroglobulin antibody [EPR4432]; Anti-alpha 2 Macroglobulin antibody [EPR4432] at 1/1000 dilution + Human plasma lysate at 10 ug.Predicted band size : 163 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - alpha 2 Macroglobulin antibody [EPR4432]; TA307812, at 1/500 dilution, staining alpha 2 Macroglobulin in paraffin-embedded Human liver by Immunohistochemistry.