OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431.
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780.
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210.
View All Citations >>
Home All anti-A2M antibodies
Anti-A2M Antibody EPR4432
Homo sapiens alpha-2-macroglobulin (A2M)
A2MD; CPAMD5; FWP007; S863-7
A synthetic peptide corresponding to residues in human Alpha 2 Macroglobulin was used as an immunogen.
Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
IHC: 1:500-1,000, WB: 1:10,000-50,000,
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. Alpha-2-macroglobulin is implicated in Alzheimer’s disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits (1).
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Western blot analysis on human plasma lysate using anti-Alpha 2 Macroglobulin RabMAb .
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Alpha 2 Macroglobulin RabMAb .