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Anti-CYB5R3 Antibody EPR3868
Also for CYB5R3 (NM_000398)
|A synthetic peptide corresponding to residues in human CYB5R3 was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100
|pH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Is unsuitable for Flow Cyt,ICC/IF or IP.
|Homo sapiens cytochrome b5 reductase 3 (CYB5R3), transcript variant 1|
Entrez Gene 1727 Human
|CYB5R3 is a cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, cholesterol biosynthesis, and drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain (1).|
|Druggable Genome Amino sugar and nucleotide sugar metabolism|
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Western blot - Anti-CYB5R3 antibody [EPR3868]; All lanes : Anti-CYB5R3 antibody [EPR3868] at 1/1000 dilution.Lane 1 : A431 cell lysate .Lane 2 : Fetal liver cell lysate.Lane 3 : HeLa cell lysate .Lane 4 : U87 MG cell lysate .Lysates/proteins at 10 ug per lane.Predicted band size : 34 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CYB5R3 antibody [EPR3868]; Immunohistochemical analysis of paraffin embedded Human testis tissue labelling CYB5R3 with TA307803 at 1/50 dilution.