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Home Antibody All anti-LCAT antibodies

Anti-LCAT Antibody EPR1383(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307800
  • Rabbit monoclonal antibody against LCAT(clone EPR1383(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400086) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for LCAT (NM_000229)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human LCAT was used as an immunogen.
Clone NameEPR1383(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:100 - 1:250; WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens lecithin-cholesterol acyltransferase (LCAT)
Alternative Namelecithin-cholesterol acyltransferase
Database LinkNP_000220
Entrez Gene 3931 Human
Entrez Gene 16816 Mouse
Entrez Gene 24530 Rat
FunctionLCAT, the lecithin cholesterol acyltransferase, is an enzyme responsible for the esterification of plasma cholesterol mediating the transfer of an acyl group from lecithin to the 3-hydroxy group of cholesterol (1). In patients with familial LCAT deficiency only trace amounts or no LCAT protein is found in plasma. LCAT reactivity is essential for normal lipoprotein metabolism and for a proper equilibrium between tissue and plasma cholesterol (2). LCAT is a soluble enzyme that converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lyso-phosphatidylcholines on the surface of high-density lipoproteins (3).
Related PathwayTransmembraneDruggable Genome Glycerophospholipid metabolism

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - LCAT antibody [EPR1383(2)]; All lanes : Anti-LCAT antibody [EPR1383(2)] at 1/1000 dilution.Lane 1 : Human serum lysate.Lane 2 : Human plasma lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 50 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - LCAT antibody [EPR1383(2)]; TA307800, at 1/250 dilution, staining LCAT in paraffin-embedded Human liver tissue by Immunohistochemistry.

 

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