Homo sapiens lecithin-cholesterol acyltransferase (LCAT)
Synonyms:
lecithin-cholesterol acyltransferase
Immunogen
A synthetic peptide corresponding to residues in human LCAT was used as an immunogen.
Buffer
Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
LCAT, the lecithin cholesterol acyltransferase, is an enzyme responsible for the esterification of plasma cholesterol mediating the transfer of an acyl group from lecithin to the 3-hydroxy group of cholesterol (1). In patients with familial LCAT deficiency only trace amounts or no LCAT protein is found in plasma. LCAT reactivity is essential for normal lipoprotein metabolism and for a proper equilibrium between tissue and plasma cholesterol (2). LCAT is a soluble enzyme that converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lyso-phosphatidylcholines on the surface of high-density lipoproteins (3).
Related Pathway
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
