OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-LRP6 antibodies

Anti-LRP6 Antibody EPR2423(2)

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307797
  • Rabbit monoclonal antibody against LRP6(clone EPR2423(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419396) , 20ug
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human LRP6 was used as an immunogen.
Clone NameEPR2423(2) IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; ICC/IF: 1:100 - 1:250
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens low density lipoprotein receptor-related protein 6 (LRP6)
Alternative NameADCAD2
Database LinkNP_002327
FunctionLRP6 (low-density lipoprotein receptor-related protein 6) is a single span transmembrane Wnt receptor that interacts with Axin to promote the Wnt-dependent accumulation of beta-catenin. Cells treated with Wnt quickly induce plasma membrane-associated LRP6 aggregates. The aggregates are phosphorylated, and then promote Axin recruitment and beta-catenin stabilization. LRP6 is internalized with caveolin and components of this endocytic pathway are required not only for Wnt-3a-induced internalization of LRP6 but also for accumulation of beta-catenin (1-2).
Related Pathway
Wnt Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-LRP6 antibody [EPR2423(2)]; All lanes : Anti-LRP6 antibody [EPR2423(2)] at 1/1000 dilution.Lane 1 : HeLa cell lysates .Lane 2 : HepG2 cell lysates .Lane 3 : 293T cell lysates .Lane 4 : Jurkat cell lysates .Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 180 kDa.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-LRP6 antibody [EPR2423(2)]; Immunofluorescence analysis of HeLa cells labelled with TA307797 at 1/100 dilution.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title