Homo sapiens protein phosphatase 3, catalytic subunit, alpha isozyme (PPP3CA), transcript variant 1
Synonyms:
CALN; CALNA; CALNA1; CCN1; CNA1; PPP2B
Immunogen
A synthetic peptide corresponding to residues near the C-terminus of human PP2B was used as an immunogen.
Buffer
Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
PP2B, the calcium- and calmodulin-dependent protein phosphatase calcineurin, has been implicated in the transduction of signals that control the hypertrophy of cardiac muscle and slow fiber gene expression in skeletal muscle. Calsarcins represent a novel family of sarcomeric proteins that link calcineurin with the contractile apparatus, thereby potentially coupling muscle activity to calcineurin activation (1). The Z-disc is a highly specialized multiprotein complex of striated muscles that serves as the interface of the sarcomere and the cytoskeleton (2).
Related Pathway
MAPK signaling pathway
Wnt Signaling Pathway
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