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Home Antibody All anti-UNC13D antibodies

Anti-UNC13D Antibody EPR4915

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307785
  • Rabbit monoclonal antibody against Munc 13-4(clone EPR4915)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403710) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for UNC13D (NM_199242)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human Munc 13-4 was used as an immunogen.
Clone NameEPR4915 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:50 - 1:100; ICC: 1:50 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens unc-13 homolog D (C. elegans) (UNC13D)
Alternative NameFHL3; HLH3; HPLH3; Munc13-4
Database LinkNP_954712
Entrez Gene 201294 Human
FunctionMunc 13-4, also known as protein unc-13 homolog D, is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis, and it is involved in the regulation of cytolytic granules secretion. Mutations in Munc 13-4 are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Munc 13-4 antibody [EPR4915]; All lanes : Anti-Munc 13-4 antibody [EPR4915] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HuT-78 cell lysate.Lane 3 : JAR cell lysate.Lane 4 : Human placenta tissue lysate.Lane 5 : Human tonsil tissue lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 123 kDa.Observed band size : 110 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Munc 13-4 antibody [EPR4915]; TA307785, at 1/50 dilution, staining Munc 13-4 in Human tonsil tissue by immunohistochemistry.

 

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