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Home Antibody All anti-MYB antibodies

Anti-MYB Antibody EPR718(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307778
  • Rabbit monoclonal antibody against c-Myb(clone EPR718(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401654) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human c-Myb was used as an immunogen.
Clone NameEPR718(2) IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens v-myb avian myeloblastosis viral oncogene homolog (MYB), transcript variant 2
Alternative Namec-myb; c-myb_CDS; Cmyb; efg
Database LinkNP_005366
Entrez Gene 4602 Human
FunctionThe c-Myb proto-oncogene is a protein involved in growth regulation and differentiation in many different cell types, but it is predominantly expressed in immature hematopoietic cells where it plays an important role in cell proliferation. c-Myb activity is directly regulated by cyclin D1 and CDKs, and it is believed that c-Myb activity is regulated during the cell cycle in hematopoietic cells (2). Therefore, disrupting c-myb function might be an effective therapeutic strategy for controlling leukemic cell growth (3). c-Myb binds to promoter sequences, such as c-Myc or Bcl-2, which are expressed in cutaneous T-cell lymphoma.
Related PathwayES Cell Differentiation/IPSStem cell - PluripotencyTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - c-Myb antibody [EPR718(2)]; All lanes : Anti-c-Myb antibody [EPR718(2)] at 1/1000 dilution.Lane 1 : Jurkat cell lysates.Lane 2 : MOLT4 cell lysates.Lysates/proteins at 10 ug per lane.Predicted band size : 72 kDa.

 

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