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Home All anti-MAP2K1 antibodies
Anti-MAP2K1 Phospho Antibody EPR3338
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for MAP2K1 (NM_002755)
OriGene Data
| A phospho-specific peptide corresponding to residues surrounding serine 298 of human MEK1 were used as an immunogen. This antibody detects MEK1 phosphorylated at serine 298. |
| EPR3338 |
Rabbit IgG |
| Human, Mouse, Rat |
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| WB, IHC, IF |
ICC: 1:100 - 250, IHC: 1:100 - 250, WB: 1:1,000-10,000, |
| Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1) |
| MAPKK1; MEK1; MKK1; PRKMK1 |
| NP_002746 |
| MEK1 and MEK2 (MAPK kinase 1/2, or ERK kinase 1/2) are mitogen-activated protein kinases that stimulate MAP kinase activity, playing a role in both cell growth and differentiation (1,2). MEK itself is activated via phosphorylation at serines 217/218 and 221/222 by upstream activator kinases, including c-raf, mos and MEK kinase (3,4). p21-activated kinases (Paks) regulate MEK-1 activity, by phosphorylating proteins at Ser(298). Mek1 S298 phosphorylation is necessary for efficient activation of MEK1 and subsequent MAPK activation (5). |
EGFR1 Signaling Pathway Focal Adhesion MAPK signaling pathway Melanogenesis Senescence and Autophagy Toll-like receptor signaling pathway |
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on HeLa cell lysate using anti-Phospho-MEK1 (pS298) RabMAb .
IHC Image
Immunohistochemical analysis of paraffin-embedded colonic carcinoma tissue using Phospho-specific anti-MEK1 RabMAb .
IF Image
Immunofluorescent staining of HeLa cells using Phospho-specific anti-MEK1 RabMAb .
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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