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Home Antibody All anti-ADA antibodies

Anti-ADA Antibody EPR4438

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307764
  • Rabbit monoclonal antibody against ADA(clone EPR4438)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424974) , 20ug Explanation
100ul 325 In Stock
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human ADA was used as an immunogen.
Clone NameEPR4438 IsotypeTissue culture supernatant
Species ReactivityRat, Human (Does not react with: Mouse) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC: 1:250 - 1:500
BufferDoes not react with Mouse. Is unsuitable for Flow Cyt or IHC-P.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens adenosine deaminase (ADA)
Alternative Nameadenosine aminohydrolase; adenosine deaminase
Database LinkNP_000013
Entrez Gene 100 Human
Entrez Gene 24165 Rat
FunctionADA is an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this protein and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia (1).
Related PathwayDruggable Genome Purine metabolismMetabolic pathwaysPrimary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - ADA antibody [EPR4438]; All lanes : Anti-ADA antibody [EPR4438] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : Human fetal thymus lysate.Lane 3 : Rat kidney tissue lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 41 kDa.Observed band size : 41 kDa.

 

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