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Anti-MYBPC3 Antibody EPR3008(2)
Also for MYBPC3 (NM_000256)
|A synthetic peptide corresponding to residues in human MYBPC3 was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens myosin binding protein C, cardiac (MYBPC3)|
|CMD1MM; CMH4; FHC; LVNC10; MYBP-C|
Entrez Gene 4607 Human
|MYBPC3 is the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. It is expressed exclusively in the heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to the modulation of cardiac contractions. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.|
|Druggable Genome Hypertrophic cardiomyopathy (HCM)Dilated cardiomyopathy|
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Western blot - MYBPC3 antibody [EPR3008(2)]; Anti-MYBPC3 antibody [EPR3008(2)] at 1/1000 dilution + Human heart lysate at 10 ug.Predicted band size : 141 kDa.