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Home Antibody All anti-MYL3 antibodies

Anti-MYL3 Antibody EPR4160

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307728
  • Rabbit monoclonal antibody against Myosin Light Chain 3(clone EPR4160)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400098) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(6)
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Also for MYL3 (NM_000258)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Myosin Light Chain 3 was used as an immunogen.
Clone NameEPR4160 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC/IF or IP.

Reference Data

Target NameHomo sapiens myosin, light chain 3, alkali; ventricular, skeletal, slow (MYL3)
Alternative NameCMH8; MLC1SB; MLC1V; VLC1
Database LinkNP_000249
FunctionMyosin is an hexamer of 2 heavy chains and 4 light chains (1). The two pairs of light chains of muscle myosins are called essential light chains (ELC) and regulatory light chains (RLC). The light chains stabilize the long alpha helical neck of the myosin head (2). Myosin Light Chain 3 is an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform (3). In addition, it is a regulatory light chain of myosin that is involved in cardiac muscle contraction (1). However, it does not bind to calcium (1). Mutations in Myosin Light Chain 3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy (3).
Related Pathway

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WB Image
Western blot - Myosin light chain 3 antibody [EPR4160]; All lanes : Anti-Myosin light chain 3 antibody [EPR4160] at 1/1000 dilution.Lane 1 : human heart muscle lysate.Lane 2 : human skeletal muscle lysate.Lysates/proteins at 10 µg/ml per lane.Predicted band size : 22 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Myosin light chain 3 antibody [EPR4160]; Immunohistochemical staining of paraffin-embedded human cardiac muscle using TA307728 at a dilution of 1/100.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Myosin light chain 3 antibody [EPR4160]; Immunohistochemical staining of paraffin-embedded human skeletal muscle tissue using TA307728 at a diltion of 1/100.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Myosin light chain 3 antibody [EPR4160](TA307728); TA307728 showing negative staining in Normal brain tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Myosin light chain 3 antibody [EPR4160](TA307728); TA307728 showing negative staining in Normal liver tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Myosin light chain 3 antibody [EPR4160](TA307728); TA307728 showing negative staining in Normal tonsil tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Myosin light chain 3 antibody [EPR4160](TA307728); TA307728 showing negative staining in Normal breast tissue.

 

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