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Home Antibody All anti-NF2 antibodies

Anti-NF2 Antibody EPR2573(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307727
  • Rabbit monoclonal antibody against Merlin(clone EPR2573(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400101) , 20ug
100ul 325 In Stock
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to the C-terminus of human Merlin was used as an immunogen.
Clone NameEPR2573(2) IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:50000 - 1:200000; IP: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens neurofibromin 2 (merlin) (NF2), transcript variant 1
Alternative NameACN; BANF; SCH
Database LinkNP_000259
FunctionMerlin is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. It has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. Merlin is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in Merlin are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities (1).
Related Pathway

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WB Image
Western blot - NF2 / Merlin antibody [EPR2573(2)]; All lanes : Anti-NF2 / Merlin antibody [EPR2573(2)] at 1/50000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : MCF7 cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : PC3 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 70 kDa.

 

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