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Anti-PTEN PHOSPHO Antibody EP2138Y


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SKU Description Amount Price Availability*  
TA307724 Rabbit monoclonal antibody against PTEN Phospho (Ser380) (clone EPR2062Y ) (Phospho-Specific) 100ul $325 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues near serine 380 of human PTEN protein.
Clone NameEP2138Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:100 - 250, IHC: 1:100 - 250, WB: 1:500 - 2000,
Predicted MW Explanation 47 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens phosphatase and tensin homolog (PTEN), transcript variant 1
Alternative Name10q23del; BZS; CWS1; DEC; GLM2; MHAM; MMAC1; PTEN1; TEP1
Database LinkNP_000305
Entrez Gene 5728 Human
Entrez Gene 19211 Mouse
Entrez Gene 50557 Rat
FunctionPTEN is a protein tyrosine phosphatase that acts as a tumor suppressor, as a lipid phosphatase that dephosphorylates the D3 position of phosphatidylinositol 3,4,5-trisphosphate and as an antagonist of the PI3k
Related PathwayPhosphataseDruggable Genome Inositol phosphate metabolismPhosphatidylinositol signaling systemp53 signaling pathwayFocal adhesionTight junctionPathways in cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - PTEN (phospho S380) antibody [EP2138Y]; All lanes : Anti-PTEN (phospho S380) antibody [EP2138Y] at 1/2000 dilution.Lane 1 : NIH3T3 cell lysate.Lane 2 : NIH3T3 cell lysate treated with AP.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit-HRP at 1/1000 dilution.Predicted band size : 47 kDa.Observed band size : 47 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PTEN (phospho S380) antibody [EP2138Y]; TA307724, at a 1/100 dilution, staining PTEN in human uterine adenocarcinoma tissue by Immunohistochemistry.


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