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Home All anti-RB1 antibodies

Anti-RB1 Phospho Antibody EPR224

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA307722
  • Rabbit monoclonal antibody against RB Phospho (pS811)(clone EPR224) (Phospho-Specific)
100ul $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
30ul
$100
$50*
In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)

OriGene Data

ImmunogenA phospho specific peptide corresponding to residues surrounding Serine 811 of human Rb was used as an immunogen. This antibody only detects Rb phosphorylated at Serine 811.
Clone NameEPR224 IsotypeRabbit IgG
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1:1,000-10,000,
BufferStore at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens retinoblastoma 1 (RB1)
Alternative NameOSRC; p105-Rb; pp110; pRb; RB
Database LinkNP_000312
FunctionRetinoblastoma tumor suppressor protein (Rb) is associated with DNA binding activity and is thought to play a significant role in controlling cell cycle progression during tumor growth (1,2). Cell cycle-dependent phosphorylation by cdks inhibits Rb binding, thus allowing cell cycle progression (3). Rb inactivation and cell cycle progression likely requires first phosphorylation by cyclin D-cdk4/6 followed by cyclin E-cdk2 phosphorylation (4).
Related Pathway
Adipogenesis
Cell cycle
Senescence and Autophagy
TGF Beta Signaling Pathway

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WB Image
Western blot analysis on Jurkat cell lysates using anti-Phospho-Rb (pS811) RabMAb .

 

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