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Anti-RB1 Antibody EP44(2)
|A synthetic peptide corresponding to residues in human Rb was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:2000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens retinoblastoma 1 (RB1)|
|OSRC; p105-Rb; pp110; pRb; RB|
|Retinoblastoma tumor suppressor protein (Rb) is associated with DNA binding activity and is thought to play a significant role in controlling cell cycle progression during tumor growth (1, 2). Cell cycle-dependent phosphorylation by cdk's inhibits Rb binding, thus allowing cell cycle progression (3). Rb inactivation and cell cycle progression likely requires first phosphorylation by cyclin D-cdk4/6 followed by cyclin E-cdk2 phosphorylation (4). |
Senescence and Autophagy
TGF Beta Signaling Pathway
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Western blot - Rb antibody [EP44(2)]; All lanes : Anti-Rb antibody [EP44(2)] at 1/1000 dilution.Lane 1 : Jurkat cell lysates.Lane 2 : K562 cell lysates.Lysates/proteins at 10 µg per lane.Predicted band size : 106 kDa.