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Anti-CYB5R3 Antibody EPR3867
Also for CYB5R3 (NM_000398)
|A synthetic peptide corresponding to residues in human CYB5R3 was used as an immunogen.|
||Tissue culture supernatant
|Rat, Human (Does not react with: Mouse)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500
|Does not react with Mouse. Is unsuitable for Flow Cyt,ICC or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt,ICC or IP.
|Homo sapiens cytochrome b5 reductase 3 (CYB5R3), transcript variant 1|
Entrez Gene 1727 Human
Entrez Gene 25035 Rat
|CYB5R3 is a cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain (1).|
|Druggable Genome Amino sugar and nucleotide sugar metabolism|
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Western blot - CYB5R3 antibody [EPR3867]; All lanes : Anti-CYB5R3 antibody [EPR3867] at 1/1000 dilution.Lane 1 : A431 cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP-labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 34 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CYB5R3 antibody [EPR3867]; TA307713 at 1/250 dilution staining CYB5R3 in paraffin-embedded Human testis tissue by Immunohistochemistry.