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Home Antibody All anti-PON1 antibodies

Anti-PON1 Antibody EPR2892

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307707
  • Rabbit monoclonal antibody against PON 1(clone EPR2892)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400156) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(5)
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Also for PON1 (NM_000446)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus in human PON 1 was used as an immunogen.
Clone NameEPR2892 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsIHC: 1: 100 - 250, IP: 1 : 10 - 100, WB: 1 : 1,000 - 10,000,
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens paraoxonase 1 (PON1)
Alternative NameESA; MVCD5; PON
Database LinkNP_000437
FunctionParaoxonase 1 (PON 1) is an esterase and lactonase that is synthesized in the liver and secreted into blood, associated exclusively with high density lipoproteins (HDL) (1, 3). It hydrolyzes the toxic oxon metabolites of several organophosphorous insecticides and nerve agents (2). This protein has been implicated in protection from atherosclerosis (2). PON 1 possesses both antioxidant and anti-inflammatory properties (1, 3). Protecting LDL and HDL from lipid peroxidation, PON 1 degrades specific oxidized cholesteryl esters and oxidized phospholipids contained in lipoproteins (1, 3, 4).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - PON1 antibody [EPR2892]; All lanes : Anti-PON1 antibody [EPR2892] at 1/1000 dilution.Lane 1 : Human plasma cell lysate.Lane 2 : ovarian cancer lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 40 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PON1 antibody [EPR2892]; TA307707, at 1/100 dilution, staining PON1 in formalin-fixed, paraffin-embedded Human liver tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PON1 antibody [EPR2892](TA307707); TA307707 showing negative staining in Skeletal muscle tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PON1 antibody [EPR2892](TA307707); TA307707 showing negative staining in Normal colon tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PON1 antibody [EPR2892](TA307707); TA307707 showing negative staining in Normal breast tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PON1 antibody [EPR2892](TA307707); TA307707 showing negative staining in Normal brain tissue.

 

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