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Home Antibody All anti-SOD1 antibodies

Anti-SOD1 Antibody EPR1726

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307705
  • Rabbit monoclonal antibody against SOD1 (clone EPR1726 )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400160) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for SOD1 (NM_000454)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SOD1 was used as an immunogen.
Clone NameEPR1726 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF: 1:200; WB: 1:100000 - 1:200000; IP: 1:10; IHC-P: 1:250 - 1:500; ICC: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens superoxide dismutase 1, soluble (SOD1)
Alternative NameALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD
Database LinkNP_000445
FunctionCu/Zn superoxide dismutase (SOD1), a major intracellular antioxidant enzyme, metabolizes superoxide radicals to molecular oxygen and hydrogen peroxide (1). SOD1 is primarily a cytosolic protein, and is ubiquitously expressed in many tissues at higher levels than in the brain and spinal cord (1, 2). The structural interplay of the conserved disulfide bond and metal-site occupancy in SOD1 is of increasing interest as these post-translational modifications are known to dramatically alter the catalytic chemistry, the subcellular localization, and the susceptibility of the protein to aggregation (3). Defective SOD is linked to motor neuron death and carries implications for understanding and possible treatment of the fatal neurodegenerative disorder familial amyotrophic lateral sclerosis (FALS) (4).
Related Pathway
Hemostasis

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WB Image
Western blot - Superoxide Dismutase 1 antibody [EPR1726]; All lanes : Anti-Superoxide Dismutase 1 antibody [EPR1726] at 1/200000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : MCF7 cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : HT29 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 16 kDa.Observed band size : 16 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Superoxide Dismutase 1 antibody [EPR1726]; TA307705 at 1/250 dilution staining Superoxide Dismutase 1 in human kidney by Immunohistochemistry, Paraffin-embedded tissue.
IF Image
Immunocytochemistry/ Immunofluorescence - Superoxide Dismutase 1 antibody [EPR1726]; TA307705 (1/200) staining Superoxide Dismutase 1 in assynchronous HeLa cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.5% Triton X-100 and counterstained with DAPI in order to highlight the nucleus. For further experimental details please refer to Abreview.

 

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