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Anti-SOD1 Antibody EPR1726


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against SOD1 (clone EPR1726 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400160) , 20ug Explanation
100ul 325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SOD1 was used as an immunogen.
Clone NameEPR1726 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF: 1:200; WB: 1:100000 - 1:200000; IP: 1:10; IHC-P: 1:250 - 1:500; ICC: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens superoxide dismutase 1, soluble (SOD1)
Alternative NameALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD
Database LinkNP_000445
Entrez Gene 6647 Human
FunctionCu/Zn superoxide dismutase (SOD1), a major intracellular antioxidant enzyme, metabolizes superoxide radicals to molecular oxygen and hydrogen peroxide (1). SOD1 is primarily a cytosolic protein, and is ubiquitously expressed in many tissues at higher levels than in the brain and spinal cord (1, 2). The structural interplay of the conserved disulfide bond and metal-site occupancy in SOD1 is of increasing interest as these post-translational modifications are known to dramatically alter the catalytic chemistry, the subcellular localization, and the susceptibility of the protein to aggregation (3). Defective SOD is linked to motor neuron death and carries implications for understanding and possible treatment of the fatal neurodegenerative disorder familial amyotrophic lateral sclerosis (FALS) (4).
Related PathwayDruggable Genome Amyotrophic lateral sclerosis (ALS)Huntington's diseasePrion diseases

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Superoxide Dismutase 1 antibody [EPR1726]; All lanes : Anti-Superoxide Dismutase 1 antibody [EPR1726] at 1/200000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : MCF7 cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : HT29 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 16 kDa.Observed band size : 16 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Superoxide Dismutase 1 antibody [EPR1726]; TA307705 at 1/250 dilution staining Superoxide Dismutase 1 in human kidney by Immunohistochemistry, Paraffin-embedded tissue.
IF Image
Immunocytochemistry/ Immunofluorescence - Superoxide Dismutase 1 antibody [EPR1726]; TA307705 (1/200) staining Superoxide Dismutase 1 in assynchronous HeLa cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.5% Triton X-100 and counterstained with DAPI in order to highlight the nucleus.


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