Home All anti-HNF4A antibodies
Anti-HNF4A Antibody EPR3648
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for HNF4A (NM_000457)
|A synthetic peptide corresponding to residues in human HNF4 Alpha was used as an immunogen.|
||FC: 1:10 - 100, ICC: 1:100 - 250, IHC: 1:100 - 250, IP: 1:10 - 100, WB: 1:1,000 - 10,000,
|Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.|
|Homo sapiens hepatocyte nuclear factor 4, alpha (HNF4A), transcript variant 2|
|HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF14|
|HNF4 (Hepatocyte Nuclear Factor 4) is a nuclear receptor protein belonging to the steroid hormone receptor superfamily. HNF4 is commonly expressed in the liver and plays a critical role in liver development by establishing and maintaining hepatocyte differentiation (1). In human, two isoforms of HNF4 exists, alpha and gamma. HNF4 alpha is transcriptionally controlled transcription factor, which binds to DNA sites required for the transcription of alpha 1- antitrypsin, Apo CIII, transthyretin genes, and HNF1 alpha (2). HNF4 alpha interacts with PGC-1 to activate gluconeogenesis, leading to lipoprotein metabolism regulation (3). HNF4 alpha defects are known to cause type I diabetes (4).|
TGF Beta Signaling Pathway
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Western blot analysis on (A) HepG2, (B) A549 and (C) SW480 cell lysates using anti-HNF4 Alpha RabMAb .
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-HNF alpha RabMAb .