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Home Antibody All anti-C1QB antibodies

Anti-C1QB Antibody EPR2981

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307700
  • Rabbit monoclonal antibody against C1q (subunit B) (clone EPR2981 )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424687) , 20ug
100ul 325 In Stock
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WB(1)
IHC(11)
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Also for C1QB (NM_000491)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human C1q (subunit B) was used as an immunogen.
Clone NameEPR2981 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:250 - 500, IHC: 1:50 - 100, WB: 1:1,000 - 5,000,
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens complement component 1, q subcomponent, B chain (C1QB)
Alternative NameOTTHUMP00000002940; complement component 1, q subcomponent, beta polypeptide; complement component C1q, B chain; complement subcomponent C1q chain B; complement component 1, q subcomponent, B chain
Database LinkNP_000482
FunctionThe complement component C1 is a protein complex that consists of six subunits of C1q. Each C1q subunit of the complex is known to bind to immune complexes, which often are deposited in the basement membrane. C1q is a versatile recognition protein that triggers activation of the classical pathway of complement, where the first step involves the binding of the globular domain of Clq to the Fc regions of aggregated IgG or IgM. The C1q globular domain is a heterotrimer of the C-terminal halves of one A, one B, and one C chain, held together mainly by non-polar interactions, with a Ca2+ ion bound at the top. A modular organization has been suggested of the globular domain, consistent with the view that A, B, and C chains are functionally autonomous modules and have distinct and differential ligand-binding properties (1-3).
Related Pathway

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WB Image
Western blot - C1QB antibody [EPR2981]; Anti-C1QB antibody [EPR2981] at 1/1000 dilution + Human plasma cell lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 26 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - C1QB antibody [EPR2981]; TA307700, at a 1/50 dilution, staining C1QB in paraffin embedded Human kidney tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal brain tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal breast tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal liver tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal stomach tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal spleen tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal brain tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal breast tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal stomach tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal liver tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal spleen tissue.

 

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