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Home Antibody All anti-C1QB antibodies

Anti-C1QB Antibody EPR2981

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307700
  • Rabbit monoclonal antibody against C1q (subunit B) (clone EPR2981 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424687) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(11)
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Also for C1QB (NM_000491)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human C1q (subunit B) was used as an immunogen.
Clone NameEPR2981 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:250 - 500, IHC: 1:50 - 100, WB: 1:1,000 - 5,000,
Predicted MW Explanation 26 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens complement component 1, q subcomponent, B chain (C1QB)
Alternative NameOTTHUMP00000002940; complement component 1, q subcomponent, beta polypeptide; complement component C1q, B chain; complement subcomponent C1q chain B; complement component 1, q subcomponent, B chain
Database LinkNP_000482
Entrez Gene 713 Human
FunctionThe complement component C1 is a protein complex that consists of six subunits of C1q. Each C1q subunit of the complex is known to bind to immune complexes, which often are deposited in the basement membrane. C1q is a versatile recognition protein that triggers activation of the classical pathway of complement, where the first step involves the binding of the globular domain of Clq to the Fc regions of aggregated IgG or IgM. The C1q globular domain is a heterotrimer of the C-terminal halves of one A, one B, and one C chain, held together mainly by non-polar interactions, with a Ca2+ ion bound at the top. A modular organization has been suggested of the globular domain, consistent with the view that A, B, and C chains are functionally autonomous modules and have distinct and differential ligand-binding properties (1-3).
Related PathwaySecreted Protein Complement and coagulation cascadesPrion diseasesSystemic lupus erythematosus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - C1QB antibody [EPR2981]; Anti-C1QB antibody [EPR2981] at 1/1000 dilution + Human plasma cell lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 26 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - C1QB antibody [EPR2981]; TA307700, at a 1/50 dilution, staining C1QB in paraffin embedded Human kidney tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal brain tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal breast tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal liver tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal stomach tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal spleen tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal brain tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal breast tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal stomach tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal liver tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-C1QB antibody [EPR2981](TA307700); TA307700 showing positive staining in Normal spleen tissue.

 

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