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Home Antibody All anti-FCGR3A antibodies

Anti-FCGR3A Antibody EPR4333

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307690
  • Rabbit monoclonal antibody against CD16a(clone EPR4333)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400194) , 20ug Explanation
100ul $325 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
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Also for FCGR3A (NM_000569)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CD16a was used as an immunogen.
Clone NameEPR4333 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:50000 - 1:20000; ICC: 1:100 - 1:250
Predicted MW Explanation 29 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens Fc fragment of IgG, low affinity IIIa, receptor (CD16a) (FCGR3A), transcript variant 1
Alternative NameCD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20
Database LinkNP_000560
Entrez Gene 2214 Human
Entrez Gene 304966 Rat
FunctionCD16a is involved in the removal of antigen-antibody complexes from the circulation, as well as other antibody-dependent responses. The receptor encoded by CD16a is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide. Mutations in CD16a have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia (1).
Related PathwaySecreted ProteinES Cell Differentiation/IPSTransmembrane Natural killer cell mediated cytotoxicityFc gamma R-mediated phagocytosisSystemic lupus erythematosus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - CD16 antibody [EPR4333]; All lanes : Anti-CD16 antibody [EPR4333] at 1/50000 dilution.Lane 1 : U937 cell lysate.Lane 2 : THP-1 cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : K562 cell lysate.Lane 5 : C6 cell lysate.Lane 6 : Raw264.7 cell lysate.Lane 7 : PC-12 cell lysates .Lysates/proteins at 10 ug per lane.Predicted band size : 29 kDa.Observed band size : 45 kDa .
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