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Anti-CD4 Antibody EPR3155(2)


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against CD4(clone EPR3155(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400209) , 20ug Explanation
100ul 325 3-7 Days
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Also for CD4 (NM_000616)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CD4 was used as an immunogen.
Clone NameEPR3155(2) IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC: 1:500 - 1:1000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens CD4 molecule (CD4), transcript variant 1
Alternative NameCD4mut
Database LinkNP_000607
Entrez Gene 920 Human
FunctionT-cell surface glycoprotein CD4 (CD4) is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is reported that CD4 regulates T-cell activation and induces the aggregation of lipid rafts. CD4 associates with LCK, binds to HIV-1 gp120 and to P4HB/PDI, and upon HIV-1 binding to the cell membrane, it is part of the P4HB/PDI-CD4-CXCR4-gp120 complex. Cell surface expression of CD4 is down-modulated by HIV-1 Envelope polyprotein gp160, which interacts with and sequesters CD4 in the endoplasmic reticulum (1).
Related PathwayES Cell Differentiation/IPSTransmembraneAdult stem cellsInduced pluripotent stem cellsDruggable Genome Cell adhesion molecules (CAMs)Antigen processing and presentationHematopoietic cell lineageT cell receptor signaling pathwayPrimary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CD4 antibody [EPR3155(2)]; All lanes : Anti-CD4 antibody [EPR3155(2)] at 1/1000 dilution.Lane 1 : Human fetal thymus lysate.Lane 2 : Human tonsil lysate.Lane 3 : PBMC lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 51 kDa.


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