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Home Antibody All anti-CHRM2 antibodies

Anti-CHRM2 Antibody EPR4568

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307672
  • Rabbit monoclonal antibody against CHRM2(clone EPR4568)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424526) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CHRM2 was used as an immunogen.
Clone NameEPR4568 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens cholinergic receptor, muscarinic 2 (CHRM2), transcript variant 4
Alternative NameHM2
Database LinkNP_000730
FunctionThe muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. CHRM2 (Muscarinic acetylcholine receptor M2) is involved in the mediation of bradycardia and causes a decrease in cardiac contractility.
Related Pathway
Signaling by GPCR

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WB Image
Western blot - Muscarinic Acetylcholine Receptor 2 antibody [EPR4568]; All lanes : Anti-Muscarinic Acetylcholine Receptor 2 antibody [EPR4568] at 1/1000 dilution.Lane 1 : SH-SY5Y lysate.Lane 2 : Fetal brain lysate.Lane 3 : U87-MG lysate.Lane 4 : Neuro-2a lysate.Lane 5 : Y79 lysates .Lysates/proteins at 10 µg per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 52 kDa.Observed band size : 52 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Muscarinic Acetylcholine Receptor 2 antibody [EPR4568]; Immunohistochemical analysis of paraffin-embedded Human brain tissue using TA307672 at 1/100.
IF Image
Immunocytochemistry/ Immunofluorescence - Muscarinic Acetylcholine Receptor 2 antibody [EPR4568]; Immunofluorescent staining of SH-SY5Y cells using TA307672 at 1/100.

 

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