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Anti-CHRM2 Antibody EPR4568
Also for CHRM2 (NM_000739)
|A synthetic peptide corresponding to residues in human CHRM2 was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt.
|Homo sapiens cholinergic receptor, muscarinic 2 (CHRM2), transcript variant 4|
|The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. CHRM2 (Muscarinic acetylcholine receptor M2) is involved in the mediation of bradycardia and causes a decrease in cardiac contractility.|
Signaling by GPCR
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Western blot - Muscarinic Acetylcholine Receptor 2 antibody [EPR4568]; All lanes : Anti-Muscarinic Acetylcholine Receptor 2 antibody [EPR4568] at 1/1000 dilution.Lane 1 : SH-SY5Y lysate.Lane 2 : Fetal brain lysate.Lane 3 : U87-MG lysate.Lane 4 : Neuro-2a lysate.Lane 5 : Y79 lysates .Lysates/proteins at 10 µg per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 52 kDa.Observed band size : 52 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Muscarinic Acetylcholine Receptor 2 antibody [EPR4568]; Immunohistochemical analysis of paraffin-embedded Human brain tissue using TA307672 at 1/100.
Immunocytochemistry/ Immunofluorescence - Muscarinic Acetylcholine Receptor 2 antibody [EPR4568]; Immunofluorescent staining of SH-SY5Y cells using TA307672 at 1/100.