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Home Antibody All anti-CHRM2 antibodies

Anti-CHRM2 Antibody EPR4568

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SKU Description Amount Price Availability*  
TA307672
  • Rabbit monoclonal antibody against CHRM2(clone EPR4568)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424526) , 20ug Explanation
100ul $325 3-7 Days

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CHRM2 was used as an immunogen.
Clone NameEPR4568 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
Predicted MW Explanation 52 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens cholinergic receptor, muscarinic 2 (CHRM2), transcript variant 4
Alternative NameHM2
Database LinkNP_000730
Entrez Gene 1129 Human
Entrez Gene 243764 Mouse
Entrez Gene 81645 Rat
FunctionThe muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. CHRM2 (Muscarinic acetylcholine receptor M2) is involved in the mediation of bradycardia and causes a decrease in cardiac contractility.
Related PathwayGPCRTransmembraneDruggable Genome Calcium signaling pathwayNeuroactive ligand-receptor interactionRegulation of actin cytoskeleton

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Muscarinic Acetylcholine Receptor 2 antibody [EPR4568]; All lanes : Anti-Muscarinic Acetylcholine Receptor 2 antibody [EPR4568] at 1/1000 dilution.Lane 1 : SH-SY5Y lysate.Lane 2 : Fetal brain lysate.Lane 3 : U87-MG lysate.Lane 4 : Neuro-2a lysate.Lane 5 : Y79 lysates .Lysates/proteins at 10 ug per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 52 kDa.Observed band size : 52 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Muscarinic Acetylcholine Receptor 2 antibody [EPR4568]; Immunohistochemical analysis of paraffin-embedded Human brain tissue using TA307672 at 1/100.
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Immunocytochemistry/ Immunofluorescence - Muscarinic Acetylcholine Receptor 2 antibody [EPR4568]; Immunofluorescent staining of SH-SY5Y cells using TA307672 at 1/100.
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