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Home Antibody All anti-CHRM2 antibodies

Anti-CHRM2 Antibody EPR4568

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307672 Rabbit monoclonal antibody against CHRM2(clone EPR4568) 100ul $325 3-7 Days
LC424526 CHRM2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CHRM2 was used as an immunogen.
Clone NameEPR4568 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application * Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
Predicted MW Explanation 52 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens cholinergic receptor, muscarinic 2 (CHRM2), transcript variant 4
Alternative NameHM2
Database LinkNP_000730
Entrez Gene 1129 Human
Entrez Gene 243764 Mouse
Entrez Gene 81645 Rat
FunctionThe muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. CHRM2 (Muscarinic acetylcholine receptor M2) is involved in the mediation of bradycardia and causes a decrease in cardiac contractility.
Related PathwayGPCRTransmembraneDruggable Genome Calcium signaling pathwayNeuroactive ligand-receptor interactionRegulation of actin cytoskeleton

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

 

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