Home All anti-CHRM2 antibodies
Anti-CHRM2 Antibody EPR4568
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Also for CHRM2 (NM_000739)
|A synthetic peptide corresponding to residues in human CHRM2 was used as an immunogen.|
|Human, Mouse, Rat
||ICC: 1:100 - 250, IHC: 1:100 - 250, IP: 1:10 - 100, WB: 1:1,000 - 10,000,
|Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.|
|Homo sapiens cholinergic receptor, muscarinic 2 (CHRM2), transcript variant 4|
|The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. CHRM2 (Muscarinic acetylcholine receptor M2) is involved in the mediation of bradycardia and causes a decrease in cardiac contractility.|
Signaling by GPCR
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Western blot analysis on (A) SH-SY5Y, (B) fetal brain, (C) U87-MG, and (D) Neuro-2a, and (E) Y79 lysates using anti-CHRM2 RabMAb .
Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-CHRM2 RabMAb .