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Home Antibody All anti-NQO1 antibodies

Anti-NQO1 Antibody EPR3310

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307660
  • Rabbit monoclonal antibody against NQO1/Quinone 1 (C-term) (clone EPR3310 )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400327) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for NQO1 (NM_000903)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to the C-terminus of human NQO1/Quinone 1 was used as an immunogen.
Clone NameEPR3310 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:2000; IP: 1:10
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IHC-P.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens NAD(P)H dehydrogenase, quinone 1 (NQO1), transcript variant 1
Alternative NameDHQU; DIA4; DTD; NMOR1; NMORI; QR1
Database LinkNP_000894
FunctionNQO1/Quinoni 1 is a flavoenzyme that catalyzes two-electron reductive metabolism and detoxification of quinones and their derivatives leading to protection of cells against redox cycling and oxidative stress (1). NQO1/Quinoni 1 is mainly cytosolic, but its nuclear presence suggests its involvement in both chemoprevention and bioactivation of DNA-damaging antitumor agents (2). NQ01/Quinoni 1 may also play a role in the bioactivation of antitumor quinones such as mitomycin C (MMC), and has been proposed to have a protective effect against cancer caused by quinones and their metabolic precursors (3-4).
Related Pathway

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WB Image
Western blot - NQO1 antibody [EPR3310]; All lanes : Anti-NQO1 antibody [EPR3310] at 1/2000 dilution.Lane 1 : MCF-7 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : A549 cell lysate.Lane 4 : HepG2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 31 kDa.Observed band size : 31 kDa.

 

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