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Home Antibody All anti-PRL antibodies

Anti-PRL Antibody EP3215

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307657
  • Rabbit monoclonal antibody against Prolactin(clone EP3215)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424443) , 20ug
100ul $325 3-7 Days
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WB(1)
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Also for PRL (NM_000948)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Prolactin was used as an immunogen.
Clone NameEP3215 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; ICC: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens prolactin (PRL), transcript variant 1
Alternative NameOTTHUMP00000017727; Prolactin
Database LinkNP_000939
FunctionProlactin (PRL) is a peptide hormone secreted from the anterior pituitary gland, primarily associated with lactation. It plays an important role in the proliferation and differentiation of cells in mammary gland development (1, 2). It also participates in the regulation of angiogenesis (3). PRL has more actions than all other pituitary hormones combined. The initial step in the action of PRL, like all other hormones, is the binding to a specific membrane receptor, the PRL receptor (PRLR). Pituitary PRL acts via a classic endocrine pathway (2). The PRL that is produced by many different cell types can act in a more direct fashion; i.e., as a growth factor, neurotransmitter or immunomodulator, in an autocrine or paracrine manner. Thus, locally produced PRL can act on adjacent cells (paracrine) or on the PRL-secreting cell itself (autocrine) in many tissues via the broad distribution of its receptors (2, 4).
Related Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway

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WB Image
Western blot - Prolactin antibody [EP3215]; All lanes : Anti-Prolactin antibody [EP3215] at 1/1000 dilution.Lane 1 : Prolactin recombinant protein at 0.01 µg.Lane 2 : Human fetal pituitary lysate at 10 µg.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 26 kDa.Observed band size : 23 kDa .

 

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