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Anti-PRL Antibody EP3215


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against Prolactin(clone EP3215)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424443) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Prolactin was used as an immunogen.
Clone NameEP3215 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; ICC: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens prolactin (PRL), transcript variant 1
Alternative NameOTTHUMP00000017727; Prolactin
Database LinkNP_000939
Entrez Gene 5617 Human
FunctionProlactin (PRL) is a peptide hormone secreted from the anterior pituitary gland, primarily associated with lactation. It plays an important role in the proliferation and differentiation of cells in mammary gland development (1, 2). It also participates in the regulation of angiogenesis (3). PRL has more actions than all other pituitary hormones combined. The initial step in the action of PRL, like all other hormones, is the binding to a specific membrane receptor, the PRL receptor (PRLR). Pituitary PRL acts via a classic endocrine pathway (2). The PRL that is produced by many different cell types can act in a more direct fashion; i.e., as a growth factor, neurotransmitter or immunomodulator, in an autocrine or paracrine manner. Thus, locally produced PRL can act on adjacent cells (paracrine) or on the PRL-secreting cell itself (autocrine) in many tissues via the broad distribution of its receptors (2, 4).
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionNeuroactive ligand-receptor interactionJak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Prolactin antibody [EP3215]; All lanes : Anti-Prolactin antibody [EP3215] at 1/1000 dilution.Lane 1 : Prolactin recombinant protein at 0.01 ug.Lane 2 : Human fetal pituitary lysate at 10 ug.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 26 kDa.Observed band size : 23 kDa .


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