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Home Antibody All anti-SUMO1 antibodies

Anti-SUMO1 Antibody EP298

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307649
  • Rabbit monoclonal antibody against SUMO-1 (clone EP298 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC423653) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(5)
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Also for SUMO1 (NM_001005781)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SUMO-1 was used as an immunogen.
Clone NameEP298 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsIHC-P: 1:100 - 1:250; WB: 1:1000
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens small ubiquitin-like modifier 1 (SUMO1), transcript variant 2
Alternative NameDAP1; GMP1; OFC10; PIC1; SENP2; SMT3; SMT3C; SMT3H3; UBL1
Database LinkNP_001005781
Entrez Gene 7341 Human
Entrez Gene 22218 Mouse
Entrez Gene 301442 Rat
FunctionSmall ubiquitin-related modifier-1 (SUMO-1), also known as SMT3, Sentrin, GMP1 UBL1 and PIC1, is a member of the ubiquitin like family (1-2). Structurally similar to ubuquitin, SUMO-1 does not mark protein for degradation (SUMOlation) but instead seems to be involved in the modulation of protein-protein interaction. It also participates in a number of cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. Like ubiquitin, SUMO-1 is covalently bound to a variety of proteins (p53, Jun, p73 alpha) via a three step enzymatic pathway (3-4), as well as requiring specific proteases to activate the protein. SUMO-1 is also known to form a complex with RanGAP1 (5).
Related Pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Sumo 1 antibody [EP298]; All lanes : Anti-Sumo 1 antibody [EP298] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HL60 cell lysate.Lane 3 : A431 cell lysate.Lane 4 : NIH3T3 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 11.5 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sumo 1 antibody [EP298]; Immunohistochemical analysis of paraffin-embedded Human papillary cell thyroid gland carcinoma tissue labelling Sumo 1 with TA307649 at 1/100 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sumo 1 antibody [EP298]; Immunohistochemical analysis of paraffin embedded Human Breast carcinoma tissue using TA307649 showing +ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Sumo 1 antibody [EP298](TA307649); Immunohistochemical analysis of paraffin embedded Human Glioma tissue using TA307649 showing +ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Sumo 1 antibody [EP298](TA307649); Immunohistochemical analysis of paraffin embedded Human Urinary bladder transitional carcinoma tissue using TA307649 showing +ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Sumo 1 antibody [EP298](TA307649); Immunohistochemical analysis of paraffin embedded normal Human tonsil tissue using TA307649 showing +ve staining.

 

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