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Home Antibody All anti-SUMO2 antibodies

Anti-SUMO2 Antibody EPR4602

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307648
  • Rabbit monoclonal antibody against SUMO-2/3(clone EPR4602)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC423659) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(2)
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Also for SUMO2 (NM_001005849)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SUMO-2/3 was used as an immunogen.
Clone NameEPR4602 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:50 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens small ubiquitin-like modifier 2 (SUMO2), transcript variant 2
Alternative NameHSMT3; Smt3A; SMT3B; SMT3H2; SUMO3
Database LinkNP_001005849
Entrez Gene 6613 Human
Entrez Gene 170930 Mouse
Entrez Gene 690244 Rat
FunctionSUMO proteins and ubiquitin posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (1). SUMO-2/3 is a ubiquitin-like protein that can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer (2). Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I; it can be promoted by an E3 ligase (2). Moreover, SUMO-2/3 is expressed predominantly in the liver (2).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Sumo 2+3 antibody [EPR4602]; All lanes : Anti-Sumo 2+3 antibody [EPR4602] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : 293T cell lysate.Lane 4 : SW480 cell lysate.Lane 5 : HL60 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 11 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sumo 2+3 antibody [EPR4602]; TA307648 at 1/100 dilution, staining Sumo 2+3 in Human colon by Immunohistochemistry, Paraffin-embedded tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Sumo 2 antibody [EPR4602]; TA307648 at 1/100 diltuion, staining Sumo 2+3 in Human hepatocellular carcinoma by Immunohistochemistry, Paraffin-embedded tissue.

 

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